Glioblastoma multiforme (GBM) is among the most aggressive forms of brain tumors, with few effective treatment options and a bleak prognosis. The current standard of care (SOC), known as the STUPP regimen, includes surgical resection, radiotherapy, and temozolomide chemotherapy. Despite this rigorous approach, median progression-free survival (PFS) and overall survival (OS) are typically low.
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