A data-driven intervention that engaged communities to rapidly deploy evidence-based practices to reduce opioid-related overdose deaths—such as increasing naloxone distribution and enhancing access to medication for opioid use disorder—did not result in a statistically significant reduction in opioid-related overdose death rates during the evaluation period, according to results from the National Institutes of Health's HEALing (Helping to End Addiction Long-Term) Communities Study.

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