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New insight into how protein TDP-43 affects gene expression in ALS and FTD

Neurodegenerative diseases, such as Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are medical conditions characterized by the progressive degradation of cells in the brain, spinal cord and nerves. Over time, these diseases cause a decline in varying mental and physical functions, such as memory and cognitive deficits or a loss of voluntary muscle control and an inability to move parts of the body.

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