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'Fingerprints' of childhood cancer treatment provide clues that may help mitigate second cancers

Scientists at St. Jude Children's Research Hospital today report how lifesaving childhood cancer treatments leave "fingerprints" on DNA, which can lead to second neoplasms (cancers or cancer-like diseases) decades later. The discovery may provide a path toward reducing long-term risks of pediatric cancer therapy by improving surveillance and early detection of secondary disease for survivors. The findings were published today in Cancer Discovery.

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